Ollier's Disease, also known as enchondromatosis, frequently occurs in the small bones in the hands and toes (phalanges) and the long bones behind the phalanges, called metatarsals. This condition is characterized by multiple enchondromas. Some form of injury or trauma to the toe results in the formation of the bony irregularity or prominence.

As with the majority of enchondromas, Ollier's Disease generally requires no treatment. Only in cases where the tumors are aggressive and begin destroying bone tissue do they require further attention, often surgical removal.